Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

Megakaryocytes, the progenitor cells of blood platelets, play a crucial role in hemostasis by residing in the bone marrow and ensuring continuous platelet production. Unlike other hematopoietic cells, megakaryocytes do not enter the blood circulation intact. They remain anchored within the bone marr...

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Autori principali:	Claire Masson, Cyril Scandola, Jean-Yves Rinckel, Fabienne Proamer, Emily Janus-Bell, Fareeha Batool, Naël Osmani, Jacky G Goetz, Léa Mallo, Nathalie Brouard, Catherine Leon, Alicia Bornert, Renaud Poincloux, Olivier Destaing, Alma Mansson, Hong Qian, Maxime Lehmann, Anita Eckly
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	eLife Sciences Publications Ltd 2025-10-01
Serie:	eLife
Soggetti:	bone marrow extracellular matrix megakaryocyte
Accesso online:	https://elifesciences.org/articles/104963
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