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FLT3-ITD with NPM1 and/or DNMT3A co-mutations in acute myeloid leukemia: prognostic significance and the role of maintenance therapy post-transplantation

FLT3-ITD, NPM1, and DNMT3A mutations are common in acute myeloid leukemia (AML). However, the prognostic role of FLT3-ITD combined with NPM1 and/or DNMT3A mutations after allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains unclear. In this retrospective study, 100 AML patients wer...

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Hlavní autoři: Ruixin Li, Jiaxin Cao, Mingyang Wang, Jinting Fan, Yang Yang, Hongye Gao, Fengjiao Wang, Donglin Yang, Rongli Zhang, Weihua Zhai, Yigeng Cao, Jialin Wei, Aiming Pang, Yi He, Sizhou Feng, Mingzhe Han, Erlie Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Health 2025-12-01
Edice:Blood Science
On-line přístup:http://journals.lww.com/10.1097/BS9.0000000000000267
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