Emerging Approaches to Profile Accessible Chromatin from Formalin-Fixed Paraffin-Embedded Sections

Nucleosomes are non-uniformly distributed across eukaryotic genomes, with stretches of ‘open’ chromatin strongly associated with transcriptionally active promoters and enhancers. Understanding chromatin accessibility patterns in normal tissue and how they are altered in pathologies can provide criti...

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Bibliografiska uppgifter

Huvudupphov:	Vishnu Udayakumaran Nair Sunitha Kumary, Bryan J. Venters, Karthikeyan Raman, Sagnik Sen, Pierre-Olivier Estève, Martis W. Cowles, Michael-Christopher Keogh, Sriharsa Pradhan
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2024-05-01
Serie:	Epigenomes
Ämnen:	chromatin FFPE nucleosome nucleosome-free region nucleosome-depleted region
Länkar:	https://www.mdpi.com/2075-4655/8/2/20
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