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Case Report: A novel KRT74 variant in an eight-year-old boy with alopecia totalis successfully treated with baricitinib

Alopecia areata is an autoimmune condition characterized by non-scarring hair loss, with genetic factors playing a significant role in disease susceptibility. We report the case of an 8-year-old boy with alopecia totalis harboring a heterozygous KRT74 variant. While his mother and brother share this...

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Principais autores: Yidong Tan, Jinxiang Yang, Xuanyi Chen, Yihang Shen, Zhe Wu, Weinan Zhou, Zhirong Yao, Jingjun Zhao, Jianying Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-07-01
coleção:Frontiers in Medicine
Assuntos:
alopecia totalis
KRT74 variant
JAK1-STAT1 pathway
leukonychia
baricitinib
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmed.2025.1574656/full
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