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Does vaccination with 4CMenB convey protection against meningococcal serogroup B strains not predicted to be covered by MATS? A study of the UK clonal complex cc269

The Meningococcal Antigen Typing System (MATS) has been developed as an hSBA surrogate to evaluate potential coverage afforded by the 4-component meningococcal serogroup B vaccine (4CMenB: Bexsero, GSK). We investigated whether the lower value of MATS coverage among invasive Meningococcus serogroup...

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Principais autores: Maria Stella, Maria Giuliani, Alessia Biolchi, Sara Tomei, Rosita De Paola, Xilian Bai, Ray Borrow, Jay Lucidarme, Rita La Gaetana, Daniela Toneatto, Mariagrazia Pizza, Laura Serino, Elena Mori, Marzia Monica Giuliani
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2020-04-01
Serier:Human Vaccines & Immunotherapeutics
Fag:
neisseria meningitidis
meningococcus serogroup b
meningococcal b vaccine
4cmenb
meningococcal antigen typing system
serum bactericidal antibody assay
Online adgang:http://dx.doi.org/10.1080/21645515.2019.1688039
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