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The complex landscape of non-coding RNAs in olaparib response and resistance

Poly(ADP-ribose) polymerase inhibitors (PARPi), such as olaparib, have revolutionized the treatment of cancers with deficiencies in homologous recombination repair (HRR), most notably those with BRCA1/2 mutations. However, the clinical efficacy of olaparib is often limited by the development of both...

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Principais autores: Fatemeh Tahamipour, Maryam Ghasemi, Akram Ghahghaei-Nezamabadi, Soudeh Ghafouri-Fard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-01-01
coleção:Cancer Treatment and Research Communications
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2468294226001255
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