A novel in vitro model of trauma-induced endotheliopathy provides a platform for studying mechanisms of coagulopathy

Abstract: Trauma-induced coagulopathy (TIC) significantly contributes to trauma-related mortality, driven by dysregulated coagulation and fibrinolysis. Endotheliopathy of trauma (EoT) is central to TIC, yet its underlying mechanisms remain unclear. Current in vitro models fail to replicate the compl...

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Bibliographic Details
Main Authors: Jeries Abu-Hanna, Gang Xu, Gael B. Morrow, Lewis Timms, Naveed Akbar, Mike Laffan, Robin P. Choudhury, Nicola Curry
Format: Artigo
Language:Inglês
Published: Elsevier 2025-11-01
Series:Blood Vessels, Thrombosis & Hemostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2950327225000440
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