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Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx.

Reactive oxygen species (ROS) play a key role in the pathogenesis of proteinuria in glomerular diseases like diabetic nephropathy. Glomerular endothelial cell (GEnC) glycocalyx covers the luminal aspect of the glomerular capillary wall and makes an important contribution to the glomerular barrier. R...

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Principais autores: Anurag Singh, Raina D Ramnath, Rebecca R Foster, Emma C Wylie, Vincent Fridén, Ishita Dasgupta, Borje Haraldsson, Gavin I Welsh, Peter W Mathieson, Simon C Satchell
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0055852&type=printable
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