Microglia in the crosstalk between peripheral and central nervous systems in Parkinson’s disease

Abstract Parkinson’s disease (PD) is increasingly recognized as a multisystem disorder involving pathological α-synuclein (α-syn) accumulation and widespread neuroimmune dysregulation. Microglia, the resident immune cells in the central nervous system (CNS), are pivotal mediators of the bidirectiona...

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Detalhes bibliográficos

Principais autores:	Tianbai Li, Tao Qiu, Fei Jiang, Huaibin Cai, Weidong Le
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	Translational Neurodegeneration
Assuntos:	Microglia Parkinson’s disease Inflammation α-Synuclein Gut microbial metabolites
Acesso em linha:	https://doi.org/10.1186/s40035-025-00531-3
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