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TIGRIS and EUPHRATES eventually join and provide new evidence: a narrative review of the polymyxin B hemoperfusion

Abstract Septic shock driven by endotoxemia is associated with high mortality despite advances in supportive care. Polymyxin B hemoperfusion (PMX-HP) selectively removes circulating endotoxin and has shown variable efficacy in randomized trials. While earlier studies, such as EUPHAS, suggested benef...

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Principais autores: Toshiaki Iba, Julie Helms, Isao Nagaoka, Michio Mineshima, Ricard Ferrer
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-11-01
Series:Journal of Intensive Care
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Acceso en liña:https://doi.org/10.1186/s40560-025-00835-6
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