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METTL3-mediated m6A modification of circGLIS3 promotes prostate cancer progression and represents a potential target for ARSI therapy

Abstract Background Circular RNAs (circRNAs) have been shown to be involved in tumorigenesis and progression. However, the role of circGLIS3 (hsa_circ_0002874) in prostate cancer (PCa) has yet not been reported. Methods Candidate circRNA were determined through comprehensive analysis of public datas...

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Principais autores: Xiaofeng Cheng, Heng Yang, Yujun Chen, Zhenhao Zeng, Yifu Liu, Xiaochen Zhou, Cheng Zhang, An Xie, Gongxian Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-08-01
Serier:Cellular & Molecular Biology Letters
Fag:
Prostate cancer
Circular RNA
M6A modification
ARSI therapy
Online adgang:https://doi.org/10.1186/s11658-024-00628-z
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