Temporal patterns of motor and nonmotor symptom emergence in Parkinson’s disease: a cluster analysis

Background: Parkinson’s disease is a heterogeneous disorder characterized by a broad spectrum of motor and nonmotor symptoms. Recent studies suggest that the order of motor and nonmotor symptom development may indicate different subtypes of Parkinson’s disease. However, the temporal occurrence patte...

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Detalhes bibliográficos

Principais autores:	Yoko Sugimura, Toru Baba, Tomoko Totsune, Hideki Oizumi, Takafumi Hasegawa, Kyoko Suzuki, Atsushi Takeda
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-01-01
coleção:	Clinical Parkinsonism & Related Disorders
Assuntos:	Parkinson’s disease Nonmotor symptom Phenotype REM sleep behavior disorders Disease progression
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2590112526000034
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