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The TKI Era in Chronic Leukemias

Tyrosine kinases are proteins involved in physiological cell functions including proliferation, differentiation, and survival. However, the dysregulation of tyrosine kinase pathways occurs in malignancy, including hematological leukemias such as chronic myeloid leukemia (CML) and chronic lymphocytic...

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Principais autores: Danilo De Novellis, Fabiana Cacace, Valeria Caprioli, William G. Wierda, Kris M. Mahadeo, Francesco Paolo Tambaro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-12-01
Serier:Pharmaceutics
Fag:
chronic myeloid leukemia (CML)
chronic lymphocytic leukemia (CLL)
BCR-ABL1-inhibitors
BTK-inhibitors
PI3K-inhibitors
targeted therapy
Online adgang:https://www.mdpi.com/1999-4923/13/12/2201
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