Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition

Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan 1 (SPOCK1) has been reported to play an oncogenic role in certain cancer types; however, the role of SPOCK1 in the progression of clear cell renal cell carcinoma (ccRCC) remains elusive. Here, higher SPOCK1 transcript and protein levels we...

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Principais autores:	Yung-Wei Lin, Yu-Ching Wen, Chi-Hao Hsiao, Feng-Ru Lai, Shun-Fa Yang, Yi-Chieh Yang, Kuo-Hao Ho, Feng-Koo Hsieh, Michael Hsiao, Wei-Jiunn Lee, Ming-Hsien Chien
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-01-01
Series:	Cells
Assuntos:	SPOCK1 metastasis clear cell renal cell carcinoma snail/slug matrix metalloproteinase-2 epithelial-to-mesenchymal transition
Acceso en liña:	https://www.mdpi.com/2073-4409/12/3/352
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