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Moderate restriction of macrophage-tropic human immunodeficiency virus type 1 by SAMHD1 in monocyte-derived macrophages.

Macrophage-tropic human immunodeficiency virus type 1 (HIV-1) strains are able to grow to high titers in human monocyte-derived macrophages. However, it was recently reported that cellular protein SAMHD1 restricts HIV-1 replication in human cells of the myeloid lineage, including monocyte-derived ma...

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Autori principali: Kahoru Taya, Emi E Nakayama, Tatsuo Shioda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090969&type=printable
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