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Interaction between α-Synuclein and Bioactive Lipids: Neurodegeneration, Disease Biomarkers and Emerging Therapies

The present review provides a comprehensive examination of the intricate dynamics between α-synuclein, a protein crucially involved in the pathogenesis of several neurodegenerative diseases, including Parkinson’s disease and multiple system atrophy, and endogenously-produced bioactive lipids, which...

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Principais autores: Chiara Sanluca, Paolo Spagnolo, Romina Mancinelli, Maria Ilenia De Bartolo, Marina Fava, Mauro Maccarrone, Simone Carotti, Eugenio Gaudio, Alessandro Leuti, Giorgio Vivacqua
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-06-01
Serier:Metabolites
Fag:
α-Synuclein
synucleinopathy
neuroinflammation
neurodegeneration
bioactive lipids
gut-to-brain axis
Online adgang:https://www.mdpi.com/2218-1989/14/7/352
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