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Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies

ABSTRACT Human metapneumovirus (HMPV) inclusion bodies (IBs) are dynamic structures required for efficient viral replication and transcription. The minimum components needed to form IB-like structures in cells are the nucleoprotein (N) and the tetrameric phosphoprotein (P). HMPV P binds to the follo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kerri Beth Boggs, Kearstin Edmonds, Nicolas Cifuentes-Munoz, Farah El Najjar, Conny Ossandón, McKenna Roe, Chao Wu, Carole L. Moncman, Trevor P. Creamer, Gaya K. Amarasinghe, Daisy W. Leung, Rebecca Ellis Dutch
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2022-06-01
Cyfres:mBio
Pynciau:
Mynediad Ar-lein:https://journals.asm.org/doi/10.1128/mbio.01099-22
Tagiau: Ychwanegu Tag
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