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Proteomic Comparison of the Cytotoxicology of Two Diastereomers of Citreamicin Reveals Differentially Activation of NF-κB Pathway

Citreamicin ε is a group of antitumor compounds produced by Streptomyces species. Cytotoxicology study of two diastereomers, citreamicin ε A and B, showed different apoptotic effects on PtK2 cells with IC50 (half-maximal inhibitory concentration) values of 0.086 and 0.025 μM, respectively. Thus, we...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Ling-Li Liu, Jin Sun, Ying Xu, Li-Sheng He, Chandramouli Kondethimmanahalli, Pei-Yuan Qian
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Frontiers Media S.A. 2020-05-01
Цуврал:Frontiers in Marine Science
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/article/10.3389/fmars.2020.00228/full
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