RNA Binding Protein YTHDF2 Inhibits Synovial Fibroblast Inflammation and Bone Injury in Rheumatoid Arthritis by Reducing the mRNA Stability of IL‐6R

ABSTRACT This study examined YTHDF2's role in modulating IL‐6R signaling to regulate synovial fibroblast inflammation and bone damage in rheumatoid arthritis (RA). Synovial tissues of RA patients were collected. Human fibroblast‐like synoviocyte (FLS), MH7A cell line, was induced with TNF‐α and tran...

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Autors principals:	Yan Zhang, Xu‐Qing Cao, Xiao‐Li Ma, Yin‐Yan Guo, Tao Zhang, Li‐Li Wu, Ya‐Shan Yang, Chun‐Fang Hao, Wei‐Li Liu, Jiang‐Tao Guo
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-08-01
Col·lecció:	Kaohsiung Journal of Medical Sciences
Matèries:	fibroblast‐like synoviocytes IL‐6R inflammation rheumatoid arthritis YTHDF2
Accés en línia:	https://doi.org/10.1002/kjm2.70010
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