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Adenylyl cyclases 1 and 8 initiate a presynaptic homeostatic response to ethanol treatment.

BACKGROUND:Although ethanol exerts widespread action in the brain, only recently has progress been made in understanding the specific events occurring at the synapse during ethanol exposure. Mice deficient in the calcium-stimulated adenylyl cyclases, AC1 and AC8 (DKO), demonstrate increased sedation...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Alana C Conti, James W Maas, Krista L Moulder, Xiaoping Jiang, Bhumy A Dave, Steven Mennerick, Louis J Muglia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2009-05-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC2682654?pdf=render
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