Dosage transmission disequilibrium test (dTDT) for linkage and association detection.

Both linkage and association studies have been successfully applied to identify disease susceptibility genes with genetic markers such as microsatellites and Single Nucleotide Polymorphisms (SNPs). As one of the traditional family-based studies, the Transmission/Disequilibrium Test (TDT) measures th...

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Autori principali:	Zhehao Zhang, Jen-Chyong Wang, William Howells, Peng Lin, Arpana Agrawal, Howard J Edenberg, Jay A Tischfield, Marc A Schuckit, Laura J Bierut, Alison Goate, John P Rice
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2013-01-01
Serie:	PLoS ONE
Accesso online:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0063526&type=printable
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