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Neddylation of protein, a new strategy of protein post-translational modification for targeted treatment of central nervous system diseases

Neddylation, a type of protein post-translational modification that links the ubiquitin-like protein NEDD8 to substrate proteins, can be involved in various significant cellular processes and generate multiple biological effects. Currently, the best-characterized substrates of neddylation are the Cu...

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Principais autores: Qian Wu, Ziang Geng, Jun Lu, Shisong Wang, Zhongxue Yu, Siqi Wang, Xiaolin Ren, Shu Guan, Tiancong Liu, Chen Zhu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-11-01
Serier:Frontiers in Neuroscience
Fag:
neddylation
central nervous system
neurology
glioma
targeted therapy
Online adgang:https://www.frontiersin.org/articles/10.3389/fnins.2024.1467562/full
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