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Three alternative promoters govern PGC-1α expression in chicken and are directly repressed by PPARγ

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a key transcriptional coactivator that orchestrates diverse physiological and pathological processes by interacting with factors such as PPARγ, PPARα, and NRFs. While extensively characterized in mammals, PGC-1α gene structure a...

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Autori principali: Jiaxin Huang, Fang Mu, Ming Lou, Fan Gao, Bolin Ning, Haoyu Luo, Xiaohong Yan, Yang Jing, Ning Wang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2026-04-01
Serie:Poultry Science
Soggetti:
Chicken
PGC-1α
Alternative promoter
PPARγ
Transcriptional regulation
Accesso online:http://www.sciencedirect.com/science/article/pii/S0032579126001082
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