Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models
Soft tissue sarcomas are a histologically heterogeneous group of rare mesenchymal cancers for which treatment options leading to increased overall survival have not improved in over two decades. The current study shows that pharmacological ascorbate (systemic high dose vitamin C achieving ⥠20 mM...
Shranjeno v:
| Principais autores: | , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2018-04-01
|
| Serija: | Redox Biology |
| Online dostop: | http://www.sciencedirect.com/science/article/pii/S2213231717305827 |
| Oznake: |
Brez oznak, prvi označite!
|