Large-scale turnover of functional transcription factor binding sites in Drosophila.
The gain and loss of functional transcription factor binding sites has been proposed as a major source of evolutionary change in cis-regulatory DNA and gene expression. We have developed an evolutionary model to study binding-site turnover that uses multiple sequence alignments to assess the evoluti...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2006-10-01
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| Serier: | PLoS Computational Biology |
| Online adgang: | https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.0020130&type=printable |
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