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Zoledronate and Clodronate affecting bone repair in non-critical defects grafted with carbonated nanostructured hydroxyapatite: an in vivo study fostering clinical reasoning

Objective: This study aimed to compare the effect of two different generations of bisphosphonates (BPs) on bone repair assisted by an alloplastic bone graft (spheres of nanostructured carbonate apatite/calcium, CHA) in a non-critical defect in the rat femur. Materials and Methods: Thirty-six fema...

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Principais autores: Gustavo Vicentis Oliveira Fernandes, Carlos Henrique Sardenberg Pereira, Adriana Terezinha Neves Novellino Alves, Alexandre Malta Rossi, José Mauro Granjeiro, Mônica Diuana Calasans-Maia, Gutemberg Gomes Alves
Format: Artigo
Sprog:Inglês
Udgivet: Medical Journals Sweden 2025-12-01
Serier:Biomaterial Investigations in Dentistry
Fag:
Bisphosphonates
clodronate
zolendronate
carbonated hydroxyapatite
femur
in vivo study
Online adgang:https://medicaljournalssweden.se/biid/article/view/45131
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