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Time-course ATAC-seq and RNA-seq analysis of porcine synovium-derived mesenchymal stem cells under in vitro osteogenic induction

Abstract Background Synovium derived mesenchymal stem cells (SMSCs) are considered promising for orthopedic application due to easy accessibility and strong differentiation potential. However, the transcription factors (TFs) that orchestrate the SMSCs osteogenic commitment, as well as the dynamic la...

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Principais autores: Shuaichen Li, Puntita Siengdee, Frieder Hadlich, Nares Trakooljul, Michael Oster, Henry Reyer, Klaus Wimmers, Siriluck Ponsuksili
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-04-01
coleção:Epigenetics & Chromatin
Assuntos:
Chromatin accessibility
Mesenchymal stem cell
Osteogenic differentiation
Transcription factor
Pig breeds
Acesso em linha:https://doi.org/10.1186/s13072-026-00668-z
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