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PDGFRα: Expression and Function during Mitral Valve Morphogenesis

Mitral valve prolapse (MVP) is a common form of valve disease and can lead to serious secondary complications. The recent identification of MVP causal mutations in primary cilia-related genes has prompted the investigation of cilia-mediated mechanisms of disease inception. Here, we investigate the r...

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Principais autores: Kelsey Moore, Diana Fulmer, Lilong Guo, Natalie Koren, Janiece Glover, Reece Moore, Cortney Gensemer, Tyler Beck, Jordan Morningstar, Rebecca Stairley, Russell A. Norris
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-03-01
coleção:Journal of Cardiovascular Development and Disease
Assuntos:
PDGFRα
mitral valve
endothelial
ERK1/2
cardiac development
Acesso em linha:https://www.mdpi.com/2308-3425/8/3/28
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