Broad-spectrum activity of bulevirtide against clinical isolates of HDV and recombinant pan-genotypic combinations of HBV/HDV

Background & Aims: Bulevirtide (BLV) is a small lipopeptide agent that specifically binds to the sodium taurocholate cotransporting polypeptide (NTCP) bile salt transporter and HBV/HDV receptor on the surface of human hepatocytes and inhibits HDV and HBV entry. As a satellite virus of HBV, HDV v...

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Autori principali:	Roberto Mateo, Simin Xu, Alex Shornikov, Tahmineh Yazdi, Yang Liu, Lindsey May, Bin Han, Dong Han, Ross Martin, Savrina Manhas, Christopher Richards, Caleb Marceau, Thomas Aeschbacher, Silvia Chang, Dmitry Manuilov, Julius Hollnberger, Stephan Urban, Tarik Asselah, Dzhamal Abdurakhmanov, Pietro Lampertico, Evguenia Maiorova, Hongmei Mo
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2023-11-01
Serie:	JHEP Reports
Soggetti:	hepatitis delta virus hepatitis Bulevirtide
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2589555923002240
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