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On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN

Alignment of the mitotic spindle to the cellular polarity axis is a prerequisite for asymmetric cell divisions. The protein network coordinating the spindle position with cortical polarity includes the molecular machinery pulling on astral microtubules, which is assembled on conserved NuMA:LGN:Gαi c...

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Détails bibliographiques
Auteurs principaux: Marina Mapelli, Cayetano Gonzalez
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2012-01-01
Collection:Open Biology
Sujets:
Accès en ligne:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120102
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