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Genetic study of the CDKN2A and CDKN2B genes in renal cell carcinoma patients

Objectives: While recent studies have demonstrated several genetic alterations are associated with pathogenesis of RCC, the significance of cyclin-dependent kinase inhibitor 2A (CDKN2A) and cyclin-dependent kinase inhibitor 2B (CDKN2B) in tumorigenesis of RCC is less clear. We investigate the distri...

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Autori principali: Nattaradee Kiatprungvech, Premsant Sangkum, Rozita Malinee, Suchada Sommaluan, Veerawat Korkiatsakul, Suchin Worawichawong, Budsaba Rerkamnuaychoke, Adcharee Kongruang, Suraida Aeesoa, Panuwat Lertsithichai, Kittinut Kijvikai, Wisoot Kongchareonsombat, Teerapong Siriboonpiputtana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2024-05-01
Serie:Practical Laboratory Medicine
Soggetti:
Renal cell carcinoma
Clear-cell RCC
CDKN2A and CDKN2B mutations
MLPA
Accesso online:http://www.sciencedirect.com/science/article/pii/S2352551724000568
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