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Dual role of calcium-activated potassium channels of high conductance: facilitator or limiter of NO-induced arterial relaxation?

AimCalcium-activated potassium channels of high conductance (BKCa channels) are important contributors to vascular smooth muscle membrane potential and thus to vascular tone. BKCa channels can promote vasodilation by facilitating vessel responses to NO. BKCa channels may also serve as limiters of th...

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Principais autores: Anastasia A. Shvetsova, Dina K. Gaynullina, Johannes Schmid, Peter Winkler, Isabella Sonsala, Rudolf Schubert
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-03-01
Serier:Frontiers in Physiology
Fag:
vasodilation
arterial smooth muscle
BK channel
nitric oxide
tail artery
saphenous artery
Online adgang:https://www.frontiersin.org/articles/10.3389/fphys.2025.1563014/full
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