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Tumor rejection in Cblb−/− mice depends on IL-9 and Th9 cells

Background Casitas B lymphoma-b (Cbl-b) is a central negative regulator of cytotoxic T and natural killer (NK) cells and functions as an intracellular checkpoint in cancer. In particular, Th9 cells support mast cell activation, promote dendritic cell recruitment, enhance the cytolytic function of cy...

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Hlavní autoři: Jenny Landsberg, Dominik Wolf, Peter Krawitz, Gottfried Baier, Peter Brossart, Oliver Schanz, Isabelle Cornez, Sowmya Parampalli Yajnanarayana, Friederike Sophie David, Sebastian Peer, Thomas Gruber, Annkristin Heine
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021-07-01
Edice:Journal for ImmunoTherapy of Cancer
On-line přístup:https://jitc.bmj.com/content/9/7/e002889.full
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