Ciclopirox Olamine Exerts Tumor-Suppressor Effects via Topoisomerase II Alpha in Lung Adenocarcinoma

BackgroundGlobally, lung cancer is one of the most malignant tumors, of which lung adenocarcinoma (LUAD) is the most common subtype, with a particularly poor prognosis. Ciclopirox olamine (CPX) is an antifungal drug and was recently identified as a potential antitumor agent. However, how CPX and its...

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Autors principals:	Jie Yin, Gang Che, Kan Jiang, Ziyang Zhou, Lingyun Wu, Mengyou Xu, Jian Liu, Senxiang Yan
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-02-01
Col·lecció:	Frontiers in Oncology
Matèries:	lung adenocarcinoma ciclopirox olamine topoisomerase II alpha DNA damage apoptosis
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2022.791916/full
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