A Box–Behnken design–assisted RP-HPLC method development and optimization for simultaneous determination of four antiviral drugs in pharmaceutical dosage forms

Abstract The advent of COVID-19 has highlighted the value of repurposing existing antiviral medications and the importance of developing efficient analytical methods to assist their quality control. Simultaneous determination of multiple agents saves time and resources in pharmaceutical analysis. Mo...

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Principais autores:	Fatma H. Ghazy, Ramzia I. El-Bagary, Samar H. Fahim, Sally T. Mahmoud
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-05-01
coleção:	Scientific Reports
Assuntos:	RP-HPLC Quality by design (QbD) Box–Behnken design (BBD) COVID-19
Acesso em linha:	https://doi.org/10.1038/s41598-026-50549-4
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