Sulodexide improves vascular permeability via glycocalyx remodelling in endothelial cells during sepsis

BackgroundDegradation of the endothelial glycocalyx is critical for sepsis-associated lung injury and pulmonary vascular permeability. We investigated whether sulodexide, a precursor for the synthesis of glycosaminoglycans, plays a biological role in glycocalyx remodeling and improves endothelial ba...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jiayun Ying, Caiyan Zhang, Yaodong Wang, Tingyan Liu, Zhenhao Yu, Kexin Wang, Weiming Chen, Yufeng Zhou, Guoping Lu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2023-08-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	sepsis sulodexide glycocalyx remodeling endothelium barrier function Syndecan-1
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172892/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!