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Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis

<p>Abstract</p> <p>Background</p> <p>Single drug use has not achieved satisfactory results in the treatment of prostate cancer, despite application of increasingly widespread targeted therapeutics. In the present study, the combined impact of the mammalian target of rapamycin (mTOR)-inhibitor RAD001...

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Бібліографічні деталі
Автори: Waaga-Gasser Ana, Tsaur Igor, Juengel Eva, Makarević Jasmina, Seibel Jens-Michael, Hudak Lukasz, Wedel Steffen, Haferkamp Axel, Blaheta Roman A
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2011-08-01
Серія:BMC Cancer
Онлайн доступ:http://www.biomedcentral.com/1471-2407/11/375
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