Large language models versus classical machine learning performance in COVID-19 mortality prediction using high-dimensional tabular data

Abstract This study compared the performance of classical feature-based machine learning models (CMLs) and large language models (LLMs) in predicting COVID-19 mortality using high-dimensional tabular data from 9,134 patients across four hospitals. Seven CML models, including XGBoost and random fores...

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Autori principali:	Mohammadreza Ghaffarzadeh-Esfahani, Mahdi Ghaffarzadeh-Esfahani, Aryan Salahi-Niri, Hossein Toreyhi, Zahra Atf, Amirali Mohsenzadeh-Kermani, Mahshad Sarikhani, Zohreh Tajabadi, Fatemeh Shojaeian, Mohammad Hassan Bagheri, Aydin Feyzi, Mohamadamin Tarighat-Payma, Narges Gazmeh, Fateme Heydari, Hossein Afshar, Amirreza Allahgholipour, Farid Alimardani, Ameneh Salehi, Naghmeh Asadimanesh, Mohammad Amin Khalafi, Hadis Shabanipour, Ali Moradi, Sajjad Hossein Zadeh, Omid Yazdani, Romina Esbati, Moozhan Maleki, Danial Samiei Nasr, Amirali Soheili, Hossein Majlesi, Saba Shahsavan, Alireza Soheilipour, Nooshin Goudarzi, Erfan Taherifard, Hamidreza Hatamabadi, Jamil S. Samaan, Thomas Savage, Ankit Sakhuja, Ali Soroush, Girish Nadkarni, Ilad Alavi Darazam, Mohamad Amin Pourhoseingholi, Seyed Amir Ahmad Safavi-Naini
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-11-01
Serie:	Scientific Reports
Soggetti:	COVID-19 mortality Large language models Machine learning Structured data Zero-shot classification Fine-tuning
Accesso online:	https://doi.org/10.1038/s41598-025-26705-7
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