QR-Code

Olfactory swab sampling optimization for α-synuclein aggregate detection in patients with Parkinson’s disease

Abstract Background In patients with Parkinson’s disease (PD), real-time quaking-induced conversion (RT-QuIC) detection of pathological α-synuclein (α-syn) in olfactory mucosa (OM) is not as accurate as in other α-synucleinopathies. It is unknown whether these variable results might be related to a...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Matilde Bongianni, Mauro Catalan, Daniela Perra, Elena Fontana, Francesco Janes, Claudio Bertolotti, Luca Sacchetto, Stefano Capaldi, Matteo Tagliapietra, Paola Polverino, Valentina Tommasini, Giulia Bellavita, Elham Ataie Kachoie, Roberto Baruca, Andrea Bernardini, Mariarosaria Valente, Michele Fiorini, Erika Bronzato, Stefano Tamburin, Laura Bertolasi, Lorenzo Brozzetti, Maria Paola Cecchini, Gianluigi Gigli, Salvatore Monaco, Paolo Manganotti, Gianluigi Zanusso
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-07-01
Schriftenreihe:Translational Neurodegeneration
Schlagworte:
Parkinson disease
Alpha-synuclein
Real-time quaking-induced conversion assay
Olfactory mucosa
Cerebrospinal fluid
Online-Zugang:https://doi.org/10.1186/s40035-022-00311-3
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge