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A flow equilibrium model controlling cytoplasmic transition metal cation pools and preventing mis-metalation as exemplified for zinc homeostasis

ABSTRACT The metal cations of the first transition period fill up their 3d orbitals from 3d5 for Mn(II) to 3d10 for Zn(II). Enzymes use these cations as cofactors and exploit their individual chemical features for important catalytic reactions. A prerequisite for this process is metalation of the re...

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Главный автор: Dietrich H. Nies
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2025-11-01
Серии:Journal of Bacteriology
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Online-ссылка:https://journals.asm.org/doi/10.1128/jb.00228-25
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