Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: Implications for neuropsychiatric diseases

Microdeletion of the human CHRNA7 gene (α7 nicotinic acetylcholine receptor, nAChR) as well as dysfunction in N-methyl-d-aspartate receptors (NMDARs) have been associated with cortical dysfunction in a broad spectrum of neurodevelopmental and neuropsychiatric disorders including schizophrenia. Howev...

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Principais autores:	Hong Lin, Fu-Chun Hsu, Bailey H. Baumann, Douglas A. Coulter, David R. Lynch
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2014-03-01
coleção:	Neurobiology of Disease
Assuntos:	α7 nicotinic acetylcholine receptor Synaptic NMDA receptor Extrasynaptic NMDA receptor d-serine Serine racemase Cortex
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996113003343
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