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An inflammatory and quiescent HSC subpopulation expands with age in humans

Abstract Aging of the blood system impacts systemic health and can be traced to hematopoietic stem cells (HSCs). Despite multiple reports on human HSC aging, a unified map detailing their molecular age-related changes is lacking. We developed a consensus map of gene expression in HSCs by integrating...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ksenia R. Safina, Basit Salik, Dylan Kotliar, Michelle Curtis, Jonathan D. Good, Chen Weng, Shawn David, Soumya Raychaudhuri, Antonia Kreso, Jennifer J. Trowbridge, Vijay G. Sankaran, Peter van Galen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2026-01-01
Cyfres:Genome Biology
Mynediad Ar-lein:https://doi.org/10.1186/s13059-026-03936-z
Tagiau: Ychwanegu Tag
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