Lysosome-dependent cell death and deregulated autophagy induced by amine-modified polystyrene nanoparticles

Nanoparticles (NPs) typically accumulate in lysosomes. However, their impact on lysosomal function, as well as autophagy, a lysosomal degradative pathway, is still not well known. We have previously reported in the 1321N1 cell line that amine-modified polystyrene (NH2-PS) NPs induce apoptosis throug...

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Detalles Bibliográficos

Autores principales:	Fengjuan Wang, Anna Salvati, Patricia Boya
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	The Royal Society 2018-04-01
Colección:	Open Biology
Materias:	cationic nanoparticles lysosomal membrane permeabilization autophagy reactive oxygen species nanotoxicity
Acceso en línea:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170271
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