Deletion of the forebrain mineralocorticoid receptor impairs social discrimination and decision-making in male, but not in female mice

Social interaction with unknown individuals requires fast processing of information to decide whether it is friend or foe. This process of discrimination and decision-making is stressful and triggers secretion of corticosterone activating mineralocorticoid receptors (MR) and glucocorticoid receptors...

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Principais autores:	Judith P Ter Horst, Maaike evan der Mark, Jiska eKentrop, Marit eArp, Rixt evan der Veen, Ronald eDe Kloet, Melly S Oitzl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2014-02-01
coleção:	Frontiers in Behavioral Neuroscience
Assuntos:	Discrimination knockout mice Sex mineralocorticoid receptor social approach social discrimination
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00026/full
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