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In Situ Cancer Vaccination and Immunovirotherapy Using Oncolytic HSV

Herpes simplex virus (HSV) can be genetically altered to acquire oncolytic properties so that oncolytic HSV (oHSV) preferentially replicates in and kills cancer cells, while sparing normal cells, and inducing anti-tumor immune responses. Over the last three decades, a better understanding of HSV gen...

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Bibliografiske detaljer
Principais autores: Nusrat Jahan, Shanawaz M. Ghouse, Robert L. Martuza, Samuel D. Rabkin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-08-01
Serier:Viruses
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Online adgang:https://www.mdpi.com/1999-4915/13/9/1740
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