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The let-7b-5p, miR-326, and miR-125a-3p are associated with left ventricular systolic dysfunction in post-myocardial infarction

BackgroundAcute ST-elevation myocardial infarction (STEMI) can lead to adverse cardiac remodeling, resulting in left ventricular systolic dysfunction (LVSd) and heart failure. Epigenetic regulators, such as microRNAs, may be involved in the physiopathology of LVSd.ObjectiveThis study explored microR...

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Principais autores: Raquel Costa Silva Dantas-Komatsu, Marina Sampaio Cruz, Paula Paccielli Freire, Rosiane Viana Zuza Diniz, Raul Hernandes Bortolin, Otávio Cabral-Marques, Kamilla Batista da Silva Souza, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata, Bruna Zavarize Reis, Igor Jurisica, Vivian Nogueira Silbiger, Andre Ducati Luchessi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-05-01
coleção:Frontiers in Cardiovascular Medicine
Assuntos:
miRNA
PBMC
myocardial infarction
left ventricular systolic dysfunction
heart failure
enrichment analysis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1151855/full
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