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Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice

The pronounced choleretic properties of 24-norUrsodeoxycholic acid (norUDCA) to induce bicarbonate-rich bile secretion have been attributed to its ability to undergo cholehepatic shunting. The goal of this study was to identify the mechanisms underlying the choleretic actions of norUDCA and the role...

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Bibliografiske detaljer
Principais autores: Jennifer K. Truong, Jianing Li, Qin Li, Kimberly Pachura, Anuradha Rao, Sanjeev Gumber, Claudia Daniela Fuchs, Andrew P. Feranchak, Saul J. Karpen, Michael Trauner, Paul A. Dawson
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2023-03-01
Serier:JCI Insight
Fag:
Online adgang:https://doi.org/10.1172/jci.insight.149360
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