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Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads

Repetitive sequences in complex eukaryote genomes can cause fragmented assemblies with incomplete gene sequences and unanchored or mispositioned contigs. Here, the authors report HERA, a method to improve genome assemblies by efficiently resolving repeats using single-molecule sequencing data.

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Huilong Du, Chengzhi Liang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2019-11-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-019-13355-3
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