A highly efficient protein corona-based proteomic analysis strategy for the discovery of pharmacodynamic biomarkers

The composition of serum is extremely complex, which complicates the discovery of new pharmacodynamic biomarkers via serum proteome for disease prediction and diagnosis. Recently, nanoparticles have been reported to efficiently reduce the proportion of high-abundance proteins and enrich low-abundanc...

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Hlavní autoři:	Yuqing Meng, Jiayun Chen, Yanqing Liu, Yongping Zhu, Yin-Kwan Wong, Haining Lyu, Qiaoli Shi, Fei Xia, Liwei Gu, Xinwei Zhang, Peng Gao, Huan Tang, Qiuyan Guo, Chong Qiu, Chengchao Xu, Xiao He, Junzhe Zhang, Jigang Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-12-01
Edice:	Journal of Pharmaceutical Analysis
Témata:	Protein corona Nanoparticles Mass spectrometry Proteomic analysis Pharmacodynamic biomarkers
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2095177922000764
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