Insightful chemistry of molecular docking studies and ADMET profiling of 4-amino-1,2,4-triazole scaffolds as potential inhibitor of DprE1 enzymes as antitubercular agents

Abstract Background Airborne transmission of the bacterial illness tuberculosis (TB) is attributed to Mycobacterium tuberculosis (Mtb). Mycobacterium tuberculosis, a multidrug-resistant strain, spreads quickly and is the cause of multidrug-resistant tuberculosis (MDRTB). A study was conducted to inv...

Повний опис

Бібліографічні деталі

Автори:	Santosh Prasad Chaudhary Kurmi, Dipanjan Karati
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Springer 2025-06-01
Серія:	Discover Chemistry
Предмети:	DprE1 enzyme Tuberculosis Toxicity prediction Retrobiocat route Bioactivity radar analysis
Онлайн доступ:	https://doi.org/10.1007/s44371-025-00208-w
Теги:	Додати тег Немає тегів, Будьте першим, хто поставить тег для цього запису!